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July 31, 2014

Flourishing Enterprise: The New Spirit of Business

New book by Weatherhead School of Management researchers sets course for economic revival

News Release: Thursday, July 31, 2014

CLEVELAND—America is on course to be surpassed economically by China and India. With a disengaged workforce and a shrinking middle class, the quality of life for the masses, long held as the American Dream, is suffering.

But a new book by a team of business management researchers from the Weatherhead School of Management at Case Western Reserve University details a progressive “people first” approach that—with minimal investment—is delivering profitability while restoring our place in a healthier and more prosperous world.

Flourishing Enterprise: The New Spirit of Business (Stanford University Press, 2014), to be released in August, provides the framework for an upcoming conference, Flourish & Prosper: The Third Global Forum for Business as an Agent of World Benefit.

The Global Forum is expected to bring together 1,000 executives, managers, and teams from companies around the world, Oct. 15-17 at Case Western Reserve, to explore how successful enterprises can achieve flourishing and prosperity for all.

The book describes vital links between paying more attention to personal well-being and concern for the planet, as well as running a successful business.

“Flourishing is the business opportunity of today—inspiring people, solving complex problems, collaborating across supply chains, and catalyzing systems change for value and profit,” said Chris Laszlo, an associate professor at the Weatherhead School and director for research and outreach at the Fowler Center for Business as an Agent of World Benefit.

As a lead author of Flourishing Enterprise, Laszlo explains the three primary takeaways from the book:
 When people are inspired by new magnitudes of purpose for business and society, they bring their deepest and best selves to work.
 In flourishing organizations, innovation emerges everywhere.
 Flourishing enterprises sustain industry leadership in the face of continual change and complexity.

Companies such as Google, General Mills, Patagonia, Fairmount Minerals, Schuberg Philis (Holland), Natura (Brazil), and Kyocera (Japan) already model many essential facets of flourishing enterprises, Laszlo said.

Nine coauthors contributed to the book, including Judy Sorum Brown, author of A Leader's Guide to Reflective Practice and The Art and Spirit of Leadership. She is a senior fellow in the School of Public Policy at the University of Maryland, Distinguished Senior Fellow at the Fowler Center and has served as a White House fellow and as vice president of the Aspen Institute.

Flourishing Enterprise includes a foreword by Peter Senge, a well-known sustainability author and senior lecturer on leadership and sustainability at MIT Sloan School of Management.

“In a business world where growth and profit is king, this book provides an inspiring alternative to what success can look like and how to achieve it,” said David Baker, senior manager of the Boeing Co. “I highly recommend it for business leaders and managers at all organizational levels.”

Important links:
Flourishing Enterprise: The New Spirit of Business (Stanford University Press)

Flourish & Prosper: The Third Global Forum for Business as an Agent of World Benefit

Posted on Think by Marvin Kropko at 06:42 PM | Comments (0) | TrackBack (0)

Entry is tagged: Official Release

July 31, 2014

CWRU graduate student Valentino Zullo finds a commonality in comics and social work

News Release: Thursday, July 31, 2014

Two unlikely professions—social work and creating superhero comics—share a common thread: Each zeros in on a person’s origin to better understand what makes them how they are, suggests a graduate student at the Case Western Reserve University social work school.

For the creators of such superheroes as Superman, The Hulk, Batman, Green Lantern, their stories are based on how the heroes got their powers, said Valentino Zullo, a comic scholar and second-year graduate student at Case Western Reserve’s Jack, Joseph and Morton Mandel School of Applied Social Sciences. And social workers search for the roots of their clients’ problems.

In fact, several graphic novelists have revealed in their work their own personal struggles with mental illnesses, Zullo contends. Are You My Mother? by Allison Bechdel depicts her own journey through psychoanalysis. Ellen Forney’s Marbles is about her struggles with manic depression. And Justin Green tells of healing his own obsessive-compulsive disorder in Binky Brown Meets the Virgin Mary.

Social work clients may benefit from similar introspection, Zullo said.

“Having people read autobiographical comics allows them to be inspired and learn that they, too, have the potential to write and illustrate their own stories,” he said.

Zullo explained how powerful it can be for a client to start writing about and drawing his or her perceptions and experiences. The pictures and words, he said, will illustrate how clients perceive the world around them.

Having the client tell stories in the form of comics, or reading comics by others with similar mental health issues, allows the social worker an entry point into understanding their stories, he said.

Zullo, 25, who grew up in Chardon, Ohio, began reading comics at age 4 to learn English. The son of immigrants from Iran and Italy, his first language was Italian.

His favorite comics were Sega’s Sonic The Hedgehog (Archie Comic imprint)—the adventures of a blue hedgehog with supersonic speed. By his teens, he had graduated to X-Men comics, but had also read entire series of comics, like Archie and others.

Zullo discovered as an undergrad at Kent State University that comics could be an actual field of study. When asked in a 17th-century literature class what he liked to read, his answer was “comics.”

Instead of ridicule, his professor told him, “Then write about the comics.”

Zullo recalled how powerful that was. “I was 19,” he said, “and no one had ever said something like that to me. I didn’t know you could write about comics.”

He earned a master’s degree in English at Bowling Green State University, where he focused on comics. He presented the talk, comics and psychiatry, at a comics conference at Dartmouth College and published academic papers on the subject.

He has also developed an interest in psychoanalysis, and recently began training at the Cleveland Psychoanalytic Center.

He plans to combine his English, social work and psychoanalysis training into a new form of treatment that he refers to as “comics and the clinic.” Eventually, he hopes to write a dissertation and book about his idea.

He has already begun sharing his interest in comics with others. Since spring, Zullo has been giving public talks about various aspects of comics at the Cleveland Public Library’s Main Library.

Starting in September, he will present a series of free, public talks expanding on his idea for using comics in social work.

And on Saturday, Aug. 2, at 2 p.m., in coordination with Cleveland hosting the Gay Games, he will explore Gay-themed comics in the talk, “Out of the Closet and into the Costume: Gay Comix.”


Posted on Think by Susan Griffith at 12:45 PM | Comments (0) | TrackBack (0)

Entry is tagged: Official Release

July 31, 2014

Researchers find cataract surgery slows dementia for Alzheimer’s patients

News Release: Thursday, July 31, 2014

Cataract surgery on Alzheimer’s disease patients slows dementia and improves their quality of life, according to clinical trials conducted by researchers at Case Western Reserve University, University Hospitals Case Medical Center and MetroHealth Medical Center in Cleveland.

The preliminary findings are the result of a five-year study funded by the National Institute on Aging that examined the benefits of cataract surgery for people with Alzheimer’s disease.

The promising results were presented recently at the Alzheimer’s Association International Conference 2014 in Copenhagen, Denmark.

Grover “Cleve” Gilmore, PhD, Dean of the Jack, Joseph and Morton Mandel School of Applied Social Sciences at Case Western Reserve, led the study. Alan Lerner, MD, from Case Western Reserve’s medical school and University Hospitals Case Medical Center, described the study’s outcomes at the conference.

Gilmore said he hopes the study’s outcomes change the health disparity for Alzheimer’s patients denied cataract surgery due to a lack of evidence of any benefit.

“We’ve shown that it does benefit them,” he said.

The researchers report that, after assessing risks and safety issues for Alzheimer’s patients, co-occurring health problems—like cataracts—should be addressed.

“This study supports the Alzheimer’s Association view that people with dementia retain, and benefit from, full health care treatment,” said Maria Carrillo, PhD, the association’s vice president of medical and science relations.

Common perceptions that Alzheimer’s patients need no extra care or shouldn’t be put through surgery “are not justified and are bad medical practice,” Carrillo said.

Gilmore’s psychological research in visual perception deficits has shown that blurred vision and problems with contrast, which can occur with aging and dementia, place many at risk for accidents, such as bumping into things and falling down stairs. And as their visual world disappears, he said, many become withdrawn.

The study’s co-investigators are: Lerner and Jon Lass, from Case Western Reserve’s Department of Ophthalmology at the medical school and University Hospitals Case Medical Center (UH); Julie Belkin and Susie Sami, from UH; Tatiana Riedel from Case Western Reserve’s Department of Psychological Sciences and Sara Debanne from the Department of Epidemiology; and Thomas Steinemann, from Case Western Reserve and MetroHealth Medical Center.

The study’s participants were recruited from UH and MetroHealth. There were 28 Alzheimer’s patients who had cataract surgery and 14 who did not. The group that had the surgery reported not only clearer vision, but that their cognitive abilities were maintained or improved as the brain worked to process and interpret information the individual can now see.

The patients weren’t the only ones to benefit from the surgery. Gilmore said caregivers reported being less stressed because the surgery allowed Alzheimer’s patients to become more mobile and independent—getting dressed, eating, moving and even driving.


Posted on Think by Susan Griffith at 12:37 PM | Comments (0) | TrackBack (0)

Entry is tagged: Official Release

July 31, 2014

$1.6 million grant backs nursing program to increase patient participation in clinical cancer trials

News Release: Thursday, July 31, 2014

Case Western Reserve University medical and nursing school researchers hope to drastically increase the number of qualified cancer patients who participate in clinical trials, a critical step in testing and developing new treatments and preventions.

For various reasons—including a lack of awareness that clinical testing exists—only approximately 5 percent of cancer patients take part in trials of experimental therapies.

As many as half of cancer patients who are eligible still don’t enroll, according to the study’s investigators, Neal Meropol, MD, from Case Western Reserve School of Medicine and University Hospitals Case Medical Center, and Barbara Daly, PhD, RN, FAAN, from CWRU’s Frances Payne Bolton School of Nursing. And both are members of the Case Comprehensive Cancer Center.

The university received a five-year, $1.6 million grant from the National Cancer Institute to develop and test a program that researchers hope will boost participation by focusing on oncology nurses to educate and inform patients about opportunities to help advance cancer research.

“We realize the culture of research does not begin and end with doctors,” Meropol said. “In fact, nurses spend more time with patients and represent an opportunity to highlight the importance of clinical trials in finding new cures for cancer.”

Clinical trials are used to assess the effectiveness of new methods of diagnosing, preventing and treating patients with, or at risk of, cancer. By participating in the testing, patients gain access to innovations in care that could improve their quality and length of life.

Because nurses spend the most time with patients, they have more opportunities to answer patients’ questions and direct them to resources to explore options offered in clinical trials.

The program

Researchers developed a program to increase participation by educating nurses on how to approach patients and discuss clinical trials as a routine treatment option.

In the first year, 30 nurses will be interviewed and another 100 will be surveyed to discover the key factors that may prevent them from sharing information with patients about clinical trials.

Based on what nurses report, researchers will develop a web-based program, called Oncology Nurse IMPACT, to address those barriers in a series of teaching videos.

A group of 1,030 nurses, recruited nationally from the Oncology Nurses Society’s 30,000 members, will participate in testing the intervention. Half will use Oncology Nurse IMPACT tailored to each nurse’s concerns. The other half will receive educational materials in the form of online text about clinical trials.

Results of the two approaches will be compared to determine which method worked best to increase discussions about trials between nurses and patients. The group receiving text information will then have the opportunity to also use Oncology Nurse IMPACT after the study is completed.

The work follows earlier studies that analyzed reservations doctors and patients have about clinical trials, said Meropol, the Dr. Lester E. Coleman, Jr., Professor of Cancer Research and Therapeutics at University Hospitals Case Medical Center and Case Western Reserve.

Researchers found doctors and patients have gaps in what they know about clinical trials, as well as some negative attitudes that prevent more patients from participating.

Among the concerns patients reported were:
• A lack of awareness about clinical trials.
• A belief that trials should only be used as a last resort.
• A fear of side effects.
• A fear they will receive a placebo instead of a treatment.
• A concern that a computer, not their physician, will select their treatment on a trial.

Daly, the Gertrude Oliva Perkins Professor in Oncology Nursing and clinical ethics director at University Hospitals Case Medical Center, noted that nurses are particularly attuned to worries that patients have and skilled in counseling and supporting patients.

Given their close relationships with patients, she said, nurses may be particularly effective in correcting misunderstandings, such as those identified in the previous research, and encouraging patients to discuss the option of trials with their oncologist.


Posted on Think by Susan Griffith at 11:40 AM | Comments (0) | TrackBack (0)

Entry is tagged: Official Release

July 28, 2014

Alumnus Professional Baseball Player Ray Mack

With the exciting news that junior pitcher Rob Winemiller was drafted by the Toronto Blue Jays we remember alumnus Ray Mack (formerly known as Mlckovsky), a former Major League player.

Ray Mlckovsky received the B.S. in Mechanical Engineering from Case School of Applied Science in 1938. He received the Honor Key and won an Athletic Medal. Mack was a member of Phi Delta Theta fraternity, Blue Key, Case Senate, Interfraternity Council, and American Society of Mechanical Engineers. As a student-athlete he earned 3 letters each in football and basketball, also winning the first Les Bale ‘09 award. Case did not have varsity baseball at the time Mack was a student, so he played amateur baseball in Cleveland.

Ray Mlckovsky (Ray Mack) in his senior year

He played in his first major league game 9/9/1938 (Cleveland vs. Detroit). He appeared in 1 other game that year and 36 in 1939 before his first complete season in 1940. In 1939 Mack played for Buffalo in the International League, teaming with Lou Boudreau for the double-play combination. He and Boudreau continued to play with each other for the Cleveland Indians. Mack was chosen for the 1940 All-Star game.

According to the Case Alumnus, “During the off-seasons, Mack held engineering jobs at the Cleveland Electric Illuminating Co. and Lamson and Sessions. In 1941, he took a part-time position in war work at Thompson Products and entered the army in 1945. In 1946, Mack rejoined the Indians and played with them throughout the season. In the winter he was traded to the New York Yankees, later played with the Newark, N.J. club and near the end of 1947, went to the Chicago Cubs. He retired from baseball in the spring of 1948 to become a sales engineer at the Browning Crane and Shovel Co.”

Mack was born 8/31/1916 in Cleveland, Ohio and died 5/7/1969 in Bucyrus Ohio. His son, Tom, played football for the Los Angeles Rams in the National Football League and was elected to the Pro Football Hall of Fame in 1999.

Posted on Recollections from the Archives by Helen Conger at 02:34 PM | Comments (5) | TrackBack (0)

Entry is tagged: People

July 28, 2014

Juan Luis Buñuel’s memoir, with entries on famed surrealist filmmaker father Luis Buñuel, appears in new publication edited by CWRU film researcher

News Release: July 28, 2014

An unedited family memoir by film director Juan Luis Buñuel, eldest son of famed Spanish surrealist filmmaker Luis Buñuel, spent 10 years in Linda Ehrlich’s closet.

With Juan Luis’ permission, Ehrlich, an associate professor of modern languages and film studies at Case Western Reserve University, edited the manuscript, recently published as Good Films, Cheap Wine, Few Friends: A Memoir (Shika Press, 2014).

“This memoir offers a first-hand look at the life of a vibrant man who has been surrounded by important figures of the 20th century, including his father, Alexander Calder, Joan Miró and Orson Welles,” writes Ehrlich.

In his memoir (originally written in English for his children), Juan Luis, 80, traces family events, from his father’s awareness of the rise of Franco’s dictatorship in Spain to exile in France, New York City, Hollywood, and, eventually, Mexico.

Following the artistic innovations of his first three films made in Europe (Un chien andalou, L’age d’or, Las Hurdes/Land Without Bread), Luis Buñuel created many of his subsequent films in Mexico, where Juan Luis spent his adolescent years.

Juan Luis learned filmmaking while working various jobs on films by Welles, Louis Malle, J.A. Bardem and his father. He wrote and directed three feature films—Expulsion of the Devil (1973), Lady with the Red Boots (1974), Leonor (1975)—and many documentaries, including a series for the United Nations Educational, Scientific and Cultural Organization (UNESCO), and two about his father’s hometown, Calanda, Spain.

The memoir details how his father’s early friendships with Salvador Dalí and the poet Federico García Lorca impacted Juan Luis’ life. Calder was like a second father who saved the family during hard times and inspired Juan Luis as a sculptor and painter.

Juan Luis’ engaging anecdotes also offer insight into the artistic world of such figures as actors Fernando Rey, Catherine Deneuve, Brigitte Bardot and Maria Félix; artists Man Ray and Rufino Tamayo; directors Ingmar Bergman and Luís Berlanga; and writers Carlos Fuentes, García Márquez and James Jones.

Readers also learn of his involvement in such important political movements as the Paris demonstrations in 1968, the Black Panthers and the reforms of Panamanian ruler Omar Torrijos.

Luis Buñuel was invited back to Spain in 1960 to make Virdiana (1961), a film that Ehrlich notes was anything but safe because of its subtle attack of religious and bourgeois hypocrisies. Juan Luis recounts smuggling the reels of his father’s completed film across the border to France, hidden beneath bullfighter’s equipment.

Once safely in France, Virdiana was entered in the Cannes Film Festival, where it won highest honors. A high-level Spanish government official, invited to speak at the ceremony, was fired the next day when the Vatican denounced the film.

The memoir’s beginning

Ehrlich met Juan Luis during a campus visit in 2004 when the Oberlin College alum was on a speaking tour in Ohio.

Messages flowed between Cleveland and Paris, where Juan Luis now calls home. One email mentioned a memoir.

Ehrlich asked to read it and received a digital copy. She urged him to make it public. With a German publisher considering it, Ehrlich shelved the manuscript.

“Last year, I wanted an intellectual challenge and thought about editing the book,” she said. Juan Luis agreed.

Thinking it would be easy, Ehrlich said she didn’t envision the 10-hour days ahead with a computer, iPad and other devices opened to French and Spanish dictionaries to verify correct spellings, dates, names and places.

Computer 22 in the Kelvin Smith Library’s Freedman Center became her unofficial “office” as she became engrossed in the book. She reorganized and redesigned the original unillustrated manuscript, with the help of Jared Bendis, the library’s creative new media officer.

She also received help from other people at the university: the Freedman Center staff, and Elena Fernández, Charlotte Sanpere-Godard and Christine Cano from the Department of Modern Languages and Literatures, and alum Corey Wright for computer skills.

Last December, Ehrlich traveled to Paris to choose photos and clarify story details with Juan Luis. When the final editing was done, she knew the project was worth the commitment.

“I read the manuscript more than 19 times and never grew tired of the stories,” she said. “Through Juan Luis’ musings about his extended family in Spain and France, I began to understand the unpretentious, fun-loving and brave nature of this remarkable group of people. It was a joy to live for a while in the ‘Buñuelian universe.’”

Posted on Think by Susan Griffith at 12:06 PM | Comments (0) | TrackBack (0)

Entry is tagged: Official Release

July 28, 2014

It takes more than practice to excel, CWRU’s new psychologist reports

News Release:July 28, 2014

Case Western Reserve University’s new assistant professor of psychology Brooke N. Macnamara, PhD, and colleagues have overturned a 20-year-old theory that people who excel in their fields are those who practiced the most.

Their findings are in this month’s online issue of Psychological Science.

“Don’t get me wrong. Practice is important,” said Macnamara, “It’s just not as important as many have thought. What does count for the skills is still unknown.”

Macnamara, who was a doctoral student at Princeton University at the time she conducted the study’s research, teamed with David Z. Hambrick, PhD, from Michigan State University, and Frederick L. Oswald, PhD, from Rice University. Each has studied how people acquire skills and become experts at what they do.

The idea that practice is the leading factor in achievement came from studies by K. Anders Ericsson, a Swedish psychologist.

In 1993, Ericsson and colleagues proposed the idea that differences in amounts of accumulated practice were the main reason why people differed in their expertise. They arrived at that conclusion by asking violin students to estimate their lifetime practice. They found that the average amount of practice estimated by the “best” students was about 10,000 hours, which was higher than the averages of less-skilled students.

Author Malcolm Gladwell further advanced that idea in Outlier: The Story of Success (Little Brown and Company 2008) by proposing the 10,000-hour rule—the notion that with 10,000 hours of practice one becomes an expert.

But Macnamara and her colleagues found that practice explained 12 percent in mastering skills in various fields, from music, sports and games to education and professions. The importance of practice in various areas was: 26 percent for games, 21 percent for music, 18 percent for sports, 4 percent for education and less than 1 percent for other professions.

Their conclusion was based on a comprehensive review of 9,331 research papers about practice relating to acquiring skills. They focused specifically on 88 papers that collected and recorded data about practice times.

The data from interviews and questionnaires about the amount of time spent practicing supported the researchers’ original assumption that something other than practice time was involved in mastering a skill.

Macnamara and colleagues also found that when amount of practice was estimated by logged hours in a journal over time—presumably a more accurate measure than when one tried to estimate lifetime practice from memory—that practice made up an even smaller percentage in acquiring the skill than the study’s average.

Her next step is to find out what factors contribute to being an expert on an instrument, playing field, in the classroom or at work. She hopes to investigate such factors as basic abilities, age when starting to learn the skill, confidence, positive or negative feedback, self-motivation and the ability to take risks.

A great practice musician could freeze up in front of an audience, she said. Yet someone less skilled but with more confidence could shine.

So practice isn’t the whole story, she said.

Posted on Think by Susan Griffith at 12:03 PM | Comments (0) | TrackBack (0)

Entry is tagged: Official Release

May 10, 2014

Social Work Licensure Review Course Set for September 12

attentive students 2 246x130.jpg

This course helps participants understand key concepts and prepare for any of the four categories of the social work licensure examination - - Bachelors, Masters, Advanced Generalist, and Clinical.

It assesses previously learned classroom material and refreshes participants' memories if they have been out of school for an extended period of time. The course seeks to help participants feel confident about their knowledge and abilities for taking the exam.

A key feature of the course is that participants study and discuss sample questions.

David Hussey, PhD, LISW-S, Associate Professor
Gerald Strom, MSW, LISW-S, Senior Instructor

The class will meet at Jack, Joseph and Morton Mandel Center for Community Studies, 11402 Bellflower Rd., on the campus of Case Western Reserve University, Cleveland OH 44106. Nearby covered parking is available.

$160 - general $140 - Mandel School alumni $75 - current Mandel School students (6 CEUs)


Register early as seating is limited.

Posted on MSASS PD/CE Online Journal by Nicole Ross Rothstein at 10:46 PM | Comments (0) | TrackBack (0)

Entry is tagged:

June 19, 2014

Submit your proposal for the upcoming Digital Scholarship Colloquium: Pedagogy & Practices

The Freedman Center for Digital Scholarship at Kelvin Smith Library will host its annual Digital Scholarship Colloquium on November 6-7, 2014. This year's colloquium will focus on digital research pedagogy and practices in the humanities, sciences and social sciences. Proposals for panels, papers and presentations that address these themes are currently being accepted.

Submission topics may include (but are not limited to) instructional methodologies and strategies for:

Please submit 250-word abstracts and technology requirements to Amanda Koziura ( by July 31, 2014. Accepted panels, papers and presentations will be notified by August 15, 2014. Please note that all presenters will be responsible for their own registration and travel costs. For more information visit

Posted on KSL News Blog by Hannah Levy at 02:29 PM | TrackBack (0)

Entry is tagged: Freedman Center

July 11, 2014

Numbers to Remember for Interlibrary Loan Services

Here are some significant numbers to keep in mind with regard to your interlibrary loan services through Kelvin Smith Library's ILLiad system...

5 -- the number of days before the due date of a loaned ILL item at which you will receive your initial reminder notification; this indicates the window until then at which you are able to request a renewal, provided the item is eligible per the lender's policy.

5 -- the maximum number of articles within the most recent 5 years of an individual publication that we may request on ILL in a single calendar year before copyright becomes an issue; requests in excess of this will then require we assume payment of often exorbitant fees per each document, to compensate the publishers.

7 -- the number of days after which the overdue status of an ILL loan starts to become critical, at which the second of two overdue notifications will be sent out; the first of these will have already been sent out the day after the item's original due date.

10 -- the number of days within which we recommend you pick up an ILL loan after we notify you that it has been received; this is not mandatory, and we will not pull and return items that have not been picked up until they actually become overdue.

14 -- the default number of additional days indicated when you submit a renewal request for an eligible loan; this is the extension we present to the lender library, but their reply may vary according to their own specific policy or local lending circumstances.

14 -- the number of days after which the overdue status of a loan now causes your ILL privileges to become blocked; you will receive an overdue notification to this effect, and functions available in your ILLiad account will be limited until you return any and all loans this many (or more) days past due.

20 -- the number of minutes after which your ILLiad online session times out, if no keystroke activity is detected; we recommend that you refresh your session regularly by clicking on the "(Your) ILLiad Page" link at the top of the Main Menu list.

30 -- the maximum number of viewing days available for electronically delivered articles; after this period, aged document files become deleted from the server during ILLiad's next scheduled automatic clean-up session.

60 -- the maximum number of days we will hold a printed article (or other non-returnable item) supplied through interlibrary loan; as we rely almost exclusively on electronic delivery, this will apply only to special instances agreed upon by ILL staff, on a case-by-case basis and with requisite justification.

We hope this information will help guide you in your use of ILLiad and ILL services. If you have questions or concerns, please contact ILL staff, by phone at (216) 368-3463 or (216) 368-3517, or by e-mail at Detailed information about interlibrary loan services and policies that might well answer your questions can also be found at our Customer Help page.

Posted on Carl's ILLiad Blog by Carl Mariani at 02:08 PM | Comments (0) | TrackBack (0)

Entry is tagged: Features | Policies | Recommendations | Services

July 10, 2014

Campus in July

Campus in summer, 1972

Many consider July the quietest month on campus - classes are not in session, people go on vacation, not many major events are held. But there’s a, perhaps, surprising amount of activity during this quiet month.

University staff with finance responsibilities are busy closing the books on the just-ended fiscal year. As the Archives is located in the same buidling as the Controller’s Office, we see them in the halls. I would never describe my colleagues as haggard, but there are signs that some of these folks may be putting in long hours. Faculty are planning fall classes, writing and continuing their research. Most of us are doing annual reports. Many of us are catching up on projects postponed from the previous academic year or getting ready for the coming academic year.

Many changes take effect in July, especially July 1, the start of the new fiscal year. Case Western Reserve University was created July 1, 1967. The Colleges, combining the undergraduate colleges Western Reserve College and Case Institute of Technology, was created July 1, 1987. It was “uncreated” five years later, again on July 1, when it was separated into the College of Arts and Sciences and the Case School of Engineering.

July often has seen the start of campus building and renovation projects. In 1985 the first phase renovation of the Emerson Physical Education Center, later renamed the Veale Convocation, Recreation and Athletic Center, started in July. Smaller projects have also been done: restoration of the windows of Amasa Stone Chapel in 1999, installation of the clock on the exterior of the Biomedical Research Building in 1992. Although, it may not be accurate to characterize a 16-foot tall, one-ton clock as a small project.

Major initiatives are frequently announced in July, even though they begin months later. Both the first and final phases of CWRU’s no smoking policies were announced in July - in 1987 and 1989. CWRU’s campus-wide Community Service Day, scheduled in September, was announced in July 2003.

Although fewer in number than during, say, April, events large and small have been held in July. In the 19th century, Commencement was often in July. More recently Party on the Quad has usually been held in July. In 1988 stamp collectors gathered on campus in July for the unveiling of a stamp honoring Dr. Harvey W. Cushing.

I’ve become more aware of these events recently as I’ve begun tweeting what I think of as Days in the Life of CWRU. It has been something of a challenge to find events for every day in July, and some days defeated me. My goal is to share some event during the university’s life for as many days as possible in the next year. The University’s history is not the sole property of the University Archives, of course, so I hope others will join in - #cwruhistory.

Posted on Recollections from the Archives by Jill Tatem at 02:49 PM | Comments (0) | TrackBack (0)

Entry is tagged: Events and Activities

July 07, 2014

Caregivers of terminal cancer patients say they can emotionally manage end-of-life treatment and decisions with help from support team, Case Western Reserve University nurse researchers find

News Release: July 7, 2014

Many caregivers of terminal cancer patients suffer depression and report regret and guilt from feeling they could have done more to eliminate side effects and relieve the pain.

So researchers from the nursing school at Case Western Reserve University devised and tested an intervention that quickly integrates a cancer support team to guide caregivers and their patients through difficult end-of-life treatment and decisions.

In the study, caregivers reported a high degree of satisfaction from having a team comprised of an advance practice nurse, social worker, a spiritual advisor and the patient’s oncologist explain what was happening and why during the dying process.

The positive outcomes of having a support team inform and allow caregivers and their patients an opportunity to think through what was important and what actions to take as the disease progressed are reported in the July issue of Oncology Nursing Forum. The National Institute of Nursing Research and the National Cancer Institute (grant: NR018717) funded the study.

The intervention’s support team got involved in end-of-life conversations with the patient and caregiver at the first diagnosis of a late-stage cancer.

In the past, many of those conversations started too late—days or weeks before the patient died, said Sara Douglas, PhD, RN, associate professor at Case Western Reserve’s Frances Payne Bolton School of Nursing and lead author.

“We owe it to the patients and caregivers to start earlier and think the choices through,” said Douglas, who conducted the research with CWRU colleague and principal investigator, Barbara Daly, PhD, RN, FAAN, professor of nursing.

The methodology

• Their intervention concept follows a larger study of 610 advanced cancer patients and their caregivers at Case Medical Center-Seidman Cancer Center in Cleveland, Ohio, between 2008 and 2012.

• From that study, the researchers analyzed data from 106 caregivers with loved ones who died from lung, gastrointestinal or gynecological cancers. They were divided into two groups: one who had received the cancer support team and one without the additional support.

• For those who received the cancer support team, a member of the team checked in with the caregiver monthly to answer questions and discuss the patient’s care and progress. At any time the caregiver had concerns, the team was available.

• Studied over 15 months, participants were asked about their mood and social supports when recruited, and again at three, nine and 15 months to gauge whether the intervention made a difference in their moods, social support and satisfaction with end-of-life care. They were also questioned after their loved one died about the patient’s care in the last week of life.

• Neither group showed changes in mood and feelings of social support. But caregivers with the aid of the cancer support team showed a higher satisfaction with end-of-life care in five areas: pain relief, managing pain, speed in treating symptoms, information about side effects and coordination of care.

The measureable benefit to grieving families of having had access to comprehensive support prior to the death of their loved one reinforces the need to include families in cancer care, Douglas said. The researchers contend support services targeting psychosocial needs of patients and families should be incorporated as routine adjuncts to cancer-directed therapy, and that this type of team-oriented approach is an effective means to do so.

“The perception that the caregiver’s loved one was well cared for can have long-term benefits in easing possible regrets that may occur after someone has died,” Douglas said.

These findings will be shared with the oncology clinical community.

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July 01, 2014

Clot-building nanoparticles raise survival rate following blast trauma

July 1, 2014

CLEVELAND—A type of artificial platelet being developed to help natural blood platelets form clots faster offers promise for saving the lives of soldiers, as well as victims of car crashes and other severe trauma.

In preclinical tests led by a Case Western Reserve University researcher, the artificial platelets, called “hemostatic nanoparticles,” when injected after blast trauma dramatically increased survival rates and showed no signs of interfering with healing or causing other complications weeks afterward.

“The nanoparticles have a huge impact on survival—not just in the short term, but in the long term,” said Erin Lavik, an associate professor of biomedical engineering at Case Western Reserve. Other researchers had raised concerns that the foreign matter would interfere with healing, or form free-floating clots, but “we saw none of that.”

The research, published in the Proceedings of the National Academy of Sciences this week, show the survival rate of mice models of blast trauma treated with the nanoparticles increased to 95, compared to 60 percent for those untreated. The release can be found at:

Also, no unwanted side effects, such as accumulation of the nanoparticles, clot formation or aberrant healing, were found during examinations one ands three weeks after the injection.

Lavik worked with Margaret M. Lashof-Sullivan, Erin Shoffstall and Kristyn T. Atkins, of Case Western Reserve; Nickolas Keane and Cynthia Bir of Wayne State University and Pamela VandeVord of Virginia Tech.

Explosions account for 79 percent of combat-related injuries and are the leading cause of battlefield deaths, according to researchers at Veterans Affairs hospitals and the federally run Uniformed Services University of the Health Sciences.

The primary blast wave, flying shrapnel and being thrown to the ground cause the lungs, liver, kidneys and other organs to hemorrhage and bleed uncontrollably.

Such uncontrolled bleeding from collisions, blows and falls is also the leading cause of death among victims age 5 to 44 in the United States.

Natural blood platelets are the key ingredient to stopping bleeding, a process called hemostasis. The process works well for typical cuts and scrapes, but can be overwhelmed with serious injuries.

Hospitals try to stem internal bleeding by giving trauma patients blood products or the hemophilia medicine called recombinant factor VIIa, but there isn’t a good option for the battlefield or accident scenes. Recombinant factor VIIa must be refrigerated, costs up to tens of thousands of dollars per treatment and can cause clots in brain and spinal cord injuries, which are common from explosions.

Lavik’s team has fine-tuned the nanoparticles to increase clotting efficiency. “They are incredibly simple… spheres with arms of peptides that react with activated blood platelets in damaged tissues to help clots form more quickly,” she said.

The particles are made from short polymer chains already approved for other uses by the U.S. Food and Drug Administration. In earlier testing, rat models injected with the nanoparticles stopped bleeding faster than untreated models.

The dry particles remained viable after two weeks on a shelf. A medic in the field or an ambulance crew would add saline, shake and inject them, the researchers say.

Further research and testing are underway. Clinical trials on humans are likely at least five years out, Lavik said.

The research was funded by the U.S. Department of Defense Grant W81XWH-11-2-0014 and the National Institutes of Health Director’s New Innovator Award DP20D007338.

Posted on Think by Kevin Mayhood at 05:54 PM | Comments (0) | TrackBack (0)

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July 01, 2014

Case Western Reserve University School of Medicine and Weatherhead School of Management to offer dual degrees in biomedical sciences and business

New graduate degrees a response to career opportunities created by changes in health care

News Release: Tuesday, July 1, 2014

To prepare students for increasing job opportunities generated by the changing health care environment, Case Western Reserve University’s School of Medicine and Weatherhead School of Management are offering two new dual graduate degrees that combine the fields of biomedical science and management.

The new dual degree programs—MBA/MS in Biochemistry and MBA/MS in Medical Physiology—start in the 2014-15 academic year. The curriculum is designed so students can complete the required coursework in three years for the MBA/MS in Biochemistry, and 2½ years for the MBA/MS Medical in Physiology.

The new dual degrees target an increasingly vital space in the job market, where translational science and business share common ground.

“Anybody with this dual degree is going to be extraordinarily marketable,” said Professor Thomas M. Nosek in the Department of Physiology and Biophysics, who helped orchestrate the new programs.
Nosek and Biochemistry Professor William Merrick each met with Associate Professor Simon Peck, in Weatherhead School of Management’s Department of Design & Innovation, to design the dual degrees. Peck is Weatherhead’s associate dean for MBA programs.

Merrick expects the dual degree to open career possibilities for biochemistry students seeking options outside of medical school, and for future medical students who realize studying business management will be valuable long-term.

“In our program,” Merrick said, “you can blend the study of bioscience and an MBA very easily. I see this as another opportunity for our students to enhance what they want to do.”

Peck said graduate students in physiology and biochemistry might be interested in entrepreneurship, the pharmaceutical industry and a range of other health-care business possibilities “that make a link-up with an MBA program a no-brainer.”

Peck said the new degree offerings are a direct response to a dynamic health-care environment. Ongoing changes are spawning:

 A growth in medical entrepreneurship and startups.
 Expansion in the medical device industry.
 A need for health care consulting.
 Demand for biomedical/business management, as the nation adapts to the Affordable Care Act.

Dual degrees are more efficient, as they allow students to complete both degrees simultaneously rather than separately. As a result, some credit hours in each program can count as electives in the other. This sharing of credits means students often earn two degrees a year earlier than they could otherwise.

The MBA/MS in Medical Physiology also offers an alternative for the first year, in which students can take the medical/science coursework online.

The dual degree option allows MBA students at the Weatherhead School the ability to enhance their professional credentials with science courses usually reserved for biomedical studies, once prerequisites for the sciences coursework are satisfied.

Capitalizing on Cleveland’s position as a global center for large research hospitals and biomedical startups, the Weatherhead School also offers a master’s degree in health care management as an evening program for working professionals.

Posted on Think by Marvin Kropko at 05:18 PM | Comments (0) | TrackBack (0)

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July 01, 2014

June 2014 Issue now online

our June issue is now online at:

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Posted on Cardiovascular Diagnosis and Therapy by Paul Schoenhagen at 01:34 PM | Comments (0) | TrackBack (0)

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June 25, 2014

CameraLends - peer-to-peer camera rental

On January 1, 2014, I left my full-time job to pursue my year-long side project. CameraLends is a peer-to-peer camera rental community. If you're familiar with Airbnb, it's a pretty similar concept. If you have camera gear that you don't use all the time (and who does!) then slap those pricy puppies on CameraLends so that others can rent it from you. Or, if you're a [hopeful] photographer, you can hop onto the site and rent gear from local photographers. Because our inventory is people powered, you have the option to do 1-day rentals (something most camera shops won't let you do) and make last minute requests. Basically, whatever the lender and renter can agree upon is kosher with us.

Worried about damage, you say? As a lender, you shouldn't be -- CameraLends has you fully covered in the case of damage. And as a lender, you can purchase a damage waiver for 15% of your reservation that covers up to $2500 worth of damage.

And Cleveland is on the map! List your gear and start earning money today!

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May 12, 2014

CEU Classes for July and August

Mandel School's Summer 2014 CEU offerings provide fresh learning for licensed human services and nonprofit professionals.

ethics and supervision remain mainstays of these offerings available at the Mandel School as well as the west-side in Westlake.

Classes are offered primarily on Fridays but also Saturday to accommodate busy work schedules.

See a list of upcoming seminars here.

Posted on MSASS PD/CE Online Journal by Michele Murphy at 11:30 AM | Comments (0) | TrackBack (0)

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June 23, 2014

ILL Books May Become Part of the KSL Collections

In case you weren't aware, some of the materials we borrow as "loans" for ILL requests are actually purchased for our retention, and may eventually be incorporated into the collections of the Kelvin Smith Library system.

Occasionally, we take advantage of certain services by various suppliers who provide us with "non-returnable" book purchases as an alternate form of interlibrary loan transaction. Alibris, Better World Books, and some other vendors offer an option to supply these items via the regular ILL request process. Sometimes, we are also able to obtain reproductions of theses and dissertations from the libraries of the respective granting institutions through ILL, when such titles cannot be lent and are not available for purchase from UMI ProQuest. Once in a great while, we may receive an offer to have very rare items--usually held only at individual foreign libraries--reproduced in print, CD-ROM, or other physical form.

Once we receive these, we process them in ILLiad as loan-type transactions, and will assign them an arbitrary but reasonable due date. Along with this, we will specify that they are allowed unlimited renewals (which will be documented in the "Notes" field for the request and be visible to the user).

What, you may ask, do we do with them after you're finished using them? Well, our normal procedure is to complete the request transactions in ILLiad (as there is no "return" process involved), and then submit the items to the appropriate subject area Research Services Librarian for consideration to be added to our own collections. In many cases they do actually become included, if it is determined they will be useful for the research interests of future library patrons (likely including the original requester). However, sometimes a granting institution library will specify that a reproduced thesis or dissertation may only be used once (by the requesting patron) for ILL purposes, and then must be discarded and not be added to any collections--as a condition of the original service agreement. Usually, in such a case the requester is also required to sign a declaration form, to confirm the title will only be used for scholarly purposes and assure it will be properly cited.

Well, we hope this information is helpful (or at least somewhat enlightening) to your understanding of part of the interlibrary loan service.

Posted on Carl's ILLiad Blog by Carl Mariani at 03:02 PM | Comments (0) | TrackBack (0)

Entry is tagged: Recommendations | Services

June 23, 2014

View new issue of KSL Connects!

For the past three years, Kelvin Smith Library's strategic plan has been the road map guiding efforts related to all aspects of our mission. From leading a campus-wide effort to deliver improved digital scholarship services, making our special collections more accessible, creating state-of-the-art facilities and hosting educational events, the Spring/Summer 2014 issue of KSL Connects takes you through our journey to be the knowledge and creativity commons of Case Western Reserve University. Browse our online edition today to learn more about the programs, services and people that are building new directions for Kelvin Smith Library.

View the magazine online today:

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Posted on KSL News Blog by Hannah Levy at 10:31 AM | TrackBack (0)

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June 19, 2014

Fall groundbreaking for first phase of expanded think[box] announced at White House “National Day of Making”

June 19, 2014

CLEVELAND—Case Western Reserve will break ground this fall on the first phase of a seven-story, 50,000 square-foot innovation hub designed to give visitors the space, technology and expert advice to imagine, prototype and, if they are so inclined, transform their creations into actual products.
The White House announced the university’s plans Wednesday as part of the administration’s National Day of Making, a celebration of America’s historic embrace of invention, whether it emerges from a tinkerer’s basement or a company’s research facility. Case Western Reserve’s initiative was among three the administration highlighted; the others were at Carnegie Mellon University and the Massachusetts Institute of Technology. In addition, Case School of Engineering Dean Jeffrey Duerk will join President Barack Obama and leaders from higher education and business later this morning for the first annual National Maker’s Faire at 1600 Pennsylvania Avenue.

Case Western Reserve’s Think[box} is a $30 million project for which the university so far has raised nearly $20 million from about 70 donors. The strong outpouring of support has allowed planners to accelerate the start of construction by breaking the project into two phases. As a result, students and other users will benefit from the much larger and well-stocked space while fundraising for the second phase continues.

The concept’s promise has been Illustrated powerfully through the pilot effort known as think[box] 1.0, a 4,500 square-foot basement space featuring equipment ranging from 3-D printers and circuit-board routers to laser cutters and a 32-square foot ShopBot—a computer-controlled device that cuts, drills, carves and more.
Opened in 2012, think[box] 1.0 has drawn 50,000 visits in the past 18 months and served as the incubator for several student start-ups, among them companies marketing a fuel-cell powered bicycle and reusable rockets. The pilot space is open to students, faculty, staff and members of the public.

Funding the effort

Generous support from accomplished alumni and area business leaders launched the pilot project and continued to drive enthusiasm—and donations—to the larger project.
Alumni Larry and Sally Sears, who committed $5.9 million to create an undergraduate lab for electrical engineering students, committed $5 million to create think[box]. Larry Sears founded Hexagram, an Ohio company that developed wireless meter-readers for utility companies.
Alumnus Barry Romich, co-founder of the Prentke Romich Co., a maker of devices that help people with speech disabilities to communicate, donated $2 million.
A. Malachi Mixon, chairman of the board of Invacare, and J.B. Richey, another alumnus and Mixon’s friend and colleague, donated $5 million. Richey created the first full-body CAT scan.

In addition, the State of Ohio this spring approved an award of $1 million to support the project.

The facility will be open to faculty, staff and students at the university and all other institutions in University Circle, as well as K-12 students, entrepreneurial groups and the public.
Expanding  opportunities
Created to support ideas, innovation and design, the new think[box] will add meeting and workspace, manufacturing equipment and experts to help guide users. The project involves renovation of the former Lincoln Storage building on campus, and its first phase includes:

 ·      Floor 1: Community; interactive presentation and workshop areas, an inventors hall of fame, social meeting spaces and more to support a range of activities focusing on users from outside the university, including K-12, students, industry groups and community groups.

 ·      Floor 2: Collaboration; open space to support generation and development of ideas. A range of informal, re-configurable spaces for users to meet, think and develop their ideas. Will include multi-media equipment to support group collaboration and expression.

 ·      Floor 3: Prototyping; A wide range of state-of-the-art digital manufacturing equipment for users to quickly turn their ideas into some form of physical object.

 ·     Floor 4: Fabrication; traditional fabrication/manufacturing workshops.

In addition to the work on these floors, the project’s first phase also includes construction of a bridge from the university’s Veale Convocation, Recreation and Athletic Center to the building’s second floor. Construction is expected to take between 12 and 16 months.

The second phase will include a large, garage-style project floor; a floor devoted to start-up assistance, including business planning, intellectual property and legal advice; and a floor for incubating start-up companies that develop both within and outside the university.
The university will announce the precise date and time of the groundbreaking later this summer.

Posted on Think by Kevin Mayhood at 06:27 PM | Comments (0) | TrackBack (0)

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June 19, 2014

Nearby satellite galaxies don’t fit standard model

Structure, behavior better explained by galaxy collisions

June 19, 2014

CLEVELAND—Satellite dwarf galaxies at the edges of the Milky Way and neighboring Andromeda defy the accepted model of galaxy formation, and recent attempts to pigeon-hole them into the model are flawed, an international team of scientists reports.

The mismatch raises questions about the accuracy of the standard model of cosmology, which is the widely accepted paradigm for the origin and evolution of the universe, the astrophysicists say.

A preprint of the research paper, accepted for publication by the Monthly Notices of the Royal Astronomical Society, is online at

The standard model, also called the “lambda cold dark matter model,” says that satellite dwarf galaxies in the Milky Way and Andromeda are expected to behave a certain way: The galaxies would form in halos of dark matter, be widely distributed and would have to move in random directions, said Marcel Pawlowski, a postdoctoral researcher in the astronomy department at Case Western Reserve University and lead author of the new study.

“But what astronomers see is different,” Pawlowski said. “We see the satellite galaxies are in a huge disk and moving in the same direction within this disk, like the planets in our solar system moving in a thin plane in one direction around the sun. That’s unexpected and could be a real problem.”

In the Milky Way, the dwarf galaxies and accompanying star clusters and streams of stars are in what’s called the Magellanic plane, or what the authors call the Vast Polar Structure; and in Andromeda, half of the satellites are in the Great Plane of Andromeda.

Pawlowski and 13 co-authors from six different countries examined three recent papers by different international teams that concluded the planar distributions of galaxies fit the standard model.

“When we compared simulations using their data to what is observed by astronomers, we found a very substantial mismatch,” Pawlowski said.

With computers, the researchers simulated mock observations of thousands of Milky Ways using the same data as the three previous papers. They found just one of a few thousand simulations matched what astronomers actually observe around the Milky Way.

“But we also have Andromeda,” Pawlowski said. “The chance to have two galaxies with such huge disks of satellite galaxies is less than one in 100,000.”

When the researchers corrected for flaws they say they found in the three studies, they could not reproduce the findings made in the respective papers.

“The standard model contains various putative ingredients— such as dark matter and dark energy —which were introduced because the model wasn’t consistent with observations,” said Benoit Famaey, a senior research associate at the University of Strasbourg in France, and co-author of the study.

Famaey and the other authors are among a small but growing number of astrophysicists who find the standard model fails to replicate what’s observed and therefore they seek alternatives.

Dark matter is thought to be an as-yet undetected matter that provides galaxies with enough mass to prevent the speed of their rotation from pulling them apart. If present, the unseen cloud of matter would be extremely unlikely to result in the planar structures seen.

The authors suggest an alternative and older explanation for the satellite dwarf galaxies: a collision between two galaxies. The collision may have ripped material from the galaxies and thrown it a great distance, much like tides on Earth. The resulting tidal dwarf galaxies are formed from the debris.

“Standard galaxies must contain dark matter, but tidal galaxies cannot contain dark matter,” said Pavel Kroupa, a co-author of the study and a professor at the University of Bonn in Germany. “There’s a very serious conflict, and the repercussion is we do not seem to have the correct theory of gravity”

The group will continue to study tidal dwarf galaxies and whether another alternative to the standard model—modified gravity—fits what they observe.

The researchers say science may initially balk at the premise but has historically embraced challenges to accepted theories, and for good reason.

“When you have a clear contradiction like this, you ought to focus on it,” said David Merritt, professor of astrophysics at Rochester Institute of Technology and co-author of the new study. “This is how progress in science is made.”

Posted on Think by Kevin Mayhood at 02:06 PM | Comments (0) | TrackBack (0)

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June 19, 2014

CWRU engineer to grow replacement tissue for torn rotator cuffs

Coaxing adult stem cells into tendons

June 19, 2014

CLEVELAND—A Case Western Reserve University engineer has won a $1.7 million National Institutes of Health (NIH) grant to grow replacement rotator cuffs and other large tendon groups to help heal injured soldiers and athletes, accident victims and an aging population that wants to remain active.

Ozan Akkus, professor of mechanical and aerospace engineering, has already devised a technique to reconstitute collagen—a building block of tendons—into tough fibers and induce adult stem cells to grow into tendons on those fibers.

“This is a concept that works on a lab bench,” Akkus said. “We will refine the concept and test the validity on an animal model.”

“Following completion of that, we may be in position for clinical applications,” he continued.

Tendons are the sinew that tie muscle to bone, enabling us to push and pull, run and jump or, in the case of the rotator cuff, throw a ball or a mundane task such as reaching up to a shelf. But the cuff is susceptible to wear and damage.

The American Academy of Orthopedic Surgeons reports that nearly 200,000 Americans require shoulder surgery to repair damaged rotator cuffs annually. The failure rate for repairs exceeds 20 percent, with the rate being highest for the largest tears.

A better fix

“A simple detachment, doctors suture back in place,” Akkus said. “But if the body or bulk of the tendon is damaged and there is not enough tendon to reattach, we need to regenerate bulk volume of the tendon.”

To achieve that, the NIH grant will allow Akkus and a team of doctors and researchers to conduct basic science and translational work during the next five years.

At the heart of tendons is collagen, which is in skin, teeth, bones and ligaments of many species and is therefore accepted by the immune system. But, “normally, when you reconstitute collagen, it’s as strong as Jell-O,” Akkus said. “For a tendon, that’s not an option.”

His lab uses electrical currents to align collagen threads, mimicking the natural tendon and making the threads dense and strong as a tendon. And his team can make threads in bulk, which would enable manufacturers to make spools of the material—enough to accommodate hundreds of thousands of surgeries.

Woven threads are sufficiently strong to be surgically handled and sutured in place and be fully load-bearing, Akkus said. “This would enable a patient to begin physical therapy and remobilization quickly,” he said.

Growing tendon tissue

The threads alone could be used as sutures to repair simple tears. But when more tendon material is needed, adult mesenchymal stem cells placed on the aligned collagen differentiate toward tendon cells without highly regulated growth factors, which also carry undesirable side effects or other chemicals.

Akkus’ lab will investigate why differentiation occurs and whether other factors, such as mechanical stress, may further induce the stem cells to develop into tendon.

They will also test whether mesenchymal stem cells in bone marrow could complete a repair. They will drill holes in bone, tie collagen scaffolds through the holes and try to coax stem cells to spread over the scaffold and grow.

If this fails, they will seed cells on a scaffold in a petri dish and allow them to grow for a few weeks before implanting the biomaterial.

The researchers believe the technology will be useful for more than tendons. For example, mesh sheets woven with controlled pore size and geometry could be used to repair hernias or urinary incontinence. Sheets of collagen could be cast in molds of an ear or nose, for replacements for patients who suffered trauma or devastating tumors.

In his tendon project, Akkus is working with graduate research assistants Mousa Younesi and Anowarul Islam. He is collaborating with James M. Anderson, professor of pathology at Case Western Reserve School of Medicine and assistant professor Robert Gillespie, orthopedic surgeon at University Hospitals Case Medical Center. Denitsa Docheva, the leader of the "TENDON" Research Group, Department of Surgery, Ludwig-Maximilians-University, Munich, Germany is consulted on the biology of stem cells and tendon cells. Three more faculty on staff at University Hospitals Case Medical Center are involved in other applications of the technology developed in Akkus’ Lab: associate professor Adonis Hijaz, urologist; and assistant professors Chad Zender and Rod Rezaee, otolaryngologists.

Posted on Think by Kevin Mayhood at 01:15 PM | Comments (0) | TrackBack (0)

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June 16, 2014

New Special Collections Exhibits at KSL

spcoll_ex_summer2014.jpg Be sure to check out KSL's new special collections exhibits! "The Alice Project" and "Science Fiction & Fantasy" are on display now in the library's (first floor) art gallery, and "The Giving Tradition" is on display in the Hatch Reading Room (second floor). The exhibits are free and open to the public during regular business hours.

The Alice Project: Last year, students of the Cleveland Institute of Art’s Illustration Department were inspired by a local book collector's exceptional collection of illustrated Lewis Carroll books. The resulting project was a book, Alice, which contains new illustrations to Lewis Carroll’s works by the students. The book and prints of the students’ work are displayed in the gallery, and additional student works can be found on display throughout the library.

Science Fiction & Fantasy: Kelvin Smith Library holds an incredibly rich collection that includes pulp serials and novels, fanzines, and first editions from the most respected authors in the genres. The collection has been built by several generous donors over the past forty years, including Francis Barry Keefe, Robert Plank, and Richard K. Wiersba. With a nod to the roots of fan culture on campus, the display also includes images of CWRU people and events that serve as inspiration to the creators of fictional realms.

The Giving Tradition: The rare book collection of a research university nearly two centuries old is the product of many minds. Scholars, librarians, collectors, and dedicated faculty have all played key parts in creating Case Western Reserve University’s special collections. The Giving Tradition highlights the contributions of a range of individuals and organizations whose books and documents have come together across time and location to form much of the Kelvin Smith Library rare book collection. Click here to explore the exhibit online!

For more information, contact

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